Instruments are nothing but sense extensions.
Not only are they extenders and enhancers, but they are also a way to remove some of the cognitive errors and biases that we introduce. Mechanical readings are an impartial, objective set of data - that data is then turned into information by subjective understandings, but the biases and inaccuracies of the measurement have been massively reduced.
We are in some way able to sense their results and we trust scientists enough to believe that their instruments are indeed working correctly and indeed measuring what they are designed to detect and that their inferences are indeed sound.
That trust is important - that's trust because of an acceptance of the effectiveness (and awareness of the limitations) of the methodology, and an understanding of the body of evidence underlying the claims. It's not blind faith, it's earned trust, and that trust is as valid from, say, a blind-person as it is from anyone else.
I agree we can detect, experiment with and accept many things that we cannot directly detect with our senses. Dark Matter is one of them, as I have stated many times.
But it requires trust and a mature inclination to accept that many things can exist that are beyond our five senses and our direct experiences. If people insist only on hard evidence for everything, they will not accept anything that they cannot sense. This includes even such a pervasive thing as Light. This was my point in this thread.
But that's just not the case. I accept the existence of electrons. I've never seen one, myself, I've not anything more than a mathematical model of their existence and nature, and yet I accept their existence, and I accept that there's hard evidence of it within published papers and peer-reviewed articles and journals. I'm as sure of the existence of electrons as I am the existence of my children - I'd not pretend we know as much about them, necessarily, but we've a reliable model.
I get what you're trying to say, that there's an element of trust in accepting scientific claims, and coupled with that is the understanding that all scientific claims are provisional.
I think you're also overlooking the cognitive bias that people have that their own senses are trustworthy - the whole 'blue/black or white/gold' dress meme(
https://en.wikipedia.org/wiki/The_dress), or the shiny legs one, if you prefer, shows that even when we do have our own senses, they are unreliable. We can measure the light frequency for a particular element with a machine and get a definitive answer, or we can sit around debating our subjective impressions - if we can't agree whether a dress is blue or white with our own eyes, why would we presume that being able to see the light is any sort of guarantee of anything more than 'there's something to investigate'.
O.